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When the purified peptide was infused into the mesodiencephalic ventricle of recipient rabbits, it reliably produced spindle and delta EEG activity characteristic of deep, restorative slow-wave sleep

Measurements of intracellular ROS After treatment with IL-22 (25 ng/ml) and/or SFN (20 nM), HaCaT cells were harvested and stained with 2 M dihydroethidium (DHE, Beyotime Institute of Biotechnology) for 30 min at 37 C in the dark

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